Avonex

On the night of my shop, I typically wake up around 4am with a fever from my Avonex.  Last night was no different.  

I got up, ate something, took some Tylenol PM and went back to sleep.  I wonder, if this medication thing is the wrong choice for me.  I know lots of people with MS who don't take meds, and I know people who MS who do.  How do I know what is the right choice for me?